# Business Development & Sales Manager **Company:** [Holostem S.r.l](http://jobs.workable.com/companies/r3DuPV1zQkxjgLVbZQJFYp.md) **Location:** Modena, Italy **Workplace:** hybrid [Apply for this job](http://jobs.workable.com/view/b89382c8-dee7-46ce-861c-2b857e6126f4) ## Description **Company Overview** Holostem Srl is a pioneering biotechnology company specialising in **Advanced Therapy Medicinal Products (ATMPs)** and regenerative medicine. The company is best known for the development and commercialization of **Holoclar®**, the **first stem cell–based ATMP to receive centralized marketing authorization from the European Medicines Agency (EMA)**. Building on the success of Holoclar®, Holostem continues to advance innovative cell‑based therapies addressing severe unmet medical needs, working closely with treatment centres, regulators, and scientific partners across Europe and internationally. **Holostem s.r.l. website** [www.holostem.com](http://www.holostem.com) **Location** Italy (with extensive European and international travel) **Reporting Line** Chief Operating Officer (COO) **Role Purpose** The Business Development & Sales Manager will drive **commercial growth and strategic expansion** for Holostem’s ATMP portfolio, including **Holoclar® and pipeline assets**. The role combines **business development, sales execution, and strategic partnership development**, with a strong focus on **treatment centre engagement**, **market access**, and **regulatory‑aware commercialisation models specific to ATMPs**. The successful candidate will act as a key interface between **commercial strategy and operational delivery**, leveraging Holostem’s experience with Holoclar® as a benchmark for excellence in ATMP market access, supply coordination, and stakeholder engagement. **Key Responsibilities** **Commercial & Business Development** - Implement **business development and commercial strategies** as agreed with the Chief Operating Officer, building on the proven commercialization framework established with **Holoclar®**. - Drive **sales performance** in assigned territories, supporting adoption of Holostem therapies at authorised and emerging treatment centres. - Identify, qualify, and onboard **new treatment centres**, ensuring readiness in line with ATMP regulatory and operational requirements. - Define, negotiate, and maintain **supply and commercial agreements** with treatment centres, reflecting the controlled supply and traceability models required for products such as Holoclar®. - Ensure **accurate forecasting and demand planning**, aligned with manufacturing capacity and clinical scheduling. **Strategic Growth & Market Expansion** - Identify and evaluate **strategic growth opportunities** across European and selected international markets, including: - Partnerships and institutional collaborations - Licensing and co‑development opportunities - Distribution and access models tailored to ATMPs - Scout and analyse **regulatory, competitive, and reimbursement environments**, using the Holoclar® experience as a reference point for risk mitigation and opportunity assessment. - Propose and implement **market‑specific strategies** that support sustainable expansion while maintaining compliance with EMA and national frameworks. **Stakeholder & Relationship Management** - Build and maintain strong relationships with **key stakeholders at treatment centres**, including clinicians, surgeons, pharmacists, procurement teams, and hospital management. - Act as a **trusted commercial and scientific partner**, supporting appropriate patient access to Holoclar® and future therapies. - Ensure consistent engagement with **key opinion leaders (KOLs)** in regenerative medicine and ATMPs. **Cross‑Functional Collaboration** - Collaborate closely with **Scientific, Regulatory, Quality, Client Services, Manufacturing, Clinical, Supply Chain, and Finance teams** to: - Align commercial opportunities with operational and manufacturing readiness - Support regulatory compliance and post‑authorization commitments linked to Holoclar® - Ensure **timely, compliant delivery** of therapies to treatment centres - Support internal decision‑making with market insights derived from field activities. **External Representation** - Represent Holostem at **international conferences, scientific congresses, partnering events, and investor meetings**, positioning Holoclar® as a reference ATMP success story. - Increase company visibility and generate **qualified commercial and strategic leads** across Europe and beyond. **Qualifications & Experience** **Education** - **PhD in Life Sciences** or a relevant scientific discipline (required). - **MBA** or equivalent business education is a plus but not mandatory. **Professional Experience** - Proven experience in **business development, sales, or strategic consultancy** within biotech, pharma, or advanced therapies. - Direct experience with **ATMPs, regenerative medicine, stem cell or cell‑based therapies**; familiarity with Holoclar® or similar hospital‑based ATMP models is a strong advantage. - Solid understanding of the **EMA regulatory framework**, including centralized authorization and post‑marketing obligations. **Technical & Business Skills** - Knowledge of **pharmaceutical and ATMP operations**, including manufacturing‑commercial interfaces. - Experience with **forecasting, contract negotiation, and partnership structuring**. - Ability to assess **complex regulatory and market environments** and translate insights into actionable commercial strategies. - Basic computer literacy; experience with CRM and reporting tools preferred. **Language Requirements** - **Fluent written and spoken English** (mandatory). - **Fluent written and spoken Italian** (mandatory). - Additional European languages are a plus. **Personal Attributes** - Strategic yet hands‑on mindset, comfortable operating in a **high‑innovation, regulated ATMP environment**. - Strong interpersonal and negotiation skills, with the ability to engage credibly with scientific, clinical, and executive stakeholders. - High level of autonomy, resilience, and willingness to travel extensively. - Strong ethical standards and commitment to patient‑centric commercialisation. **What Holostem Offers** - A pivotal role in a company with a **landmark ATMP success story (Holoclar®)** and an expanding pipeline. - Exposure to cutting‑edge regenerative medicine and advanced cell‑based therapies. - Direct interaction with senior leadership and influence on commercial and corporate strategy. - Competitive compensation package aligned with experience and performance. **Privacy** [Privacy Policy - Holostem S.r.l.](https://www.holostem.com/privacy-policy/) **Application** Application must be submitted by the 10th May 2026 to the following link: [https://apply.workable.com/](https://apply.workable.com/) The position is open to both genders (L.903/77 – D.Lgs. n.198/2006)